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Nov 17, 2022

Let's learn more about Great Burdock Fruit Extract?


Part1. What is Great Burdock Fruit Extract?

Burdock fruit extract is the water extract and alcohol extract of Arctium lappa L.a composite plant, and its main components are arctiin and so on. It has the effects of evacuating wind-heat, clearing rash and relieving sore throat, detoxifying and reducing swelling. Cure mainly wind-heat cough, sore throat, rash impenetrable, rubella itching.


Part2. Main ingredients

Arctiin (Aretiin), arctigenin (I), lappaolA, lappaolC, phenylpropanoids and their compounds, bithiophenes and their guaiacol ester derivatives, triterpenes, fatty acids and sterols, and Alkenyne derivatives, amino acids, fatty oils, vitamins, etc.


Part3. Pharmacological activity

1. Pharmacology of traditional Chinese medicine

[nature and flavor] hard, cool.

[return through] enters lung, stomach warp.

[Efficacy] Dispelling wind and dissipating heat, clearing lung and clearing rash, detoxifying and relieving sore throat.

[Indications] Cough due to wind-heat, sore throat, opaque rash, itchy rubella, mumps, erysipelas, carbuncle and sore.

2. Pharmacological action of the extract

1) Antibacterial effect:

Burdock fruit water infusion has different degrees of inhibitory effects on various pathogenic fungi such as Trichophyton concentricum, Microsporum audouin, Epidermophyton inguinale, and Nocardia star in test tubes. 100% water decoction has inhibitory effect on Staphylococcus aureus.

2) Anticancer effect:

The crude extract of Arctium Fructus is selectively toxic, and a lower amount can inhibit the proliferation of cancer cells and make tumor cells approach normal cells.

3) Effects on immune function:

Burdock fruit extract can enhance the immune function of the body, significantly increase the transformation rate of lymphocytes in normal mice and the positive rate of α-acetase in mice, and significantly increase the formation of cells in the body , to increase the phagocytic function of mouse macrophages.

4) Anti-nephropathy effect:

Intraperitoneal injection of arctigenin can resist nephropathy in rats caused by aminonucleosides, reduce urinary protein excretion, and improve serum biochemical indicators. Antagonism, and improve hypercholesterolemia; oral administration, can improve urine protein; intravenous injection can inhibit the rise of N-acetyl-β-glucosaminidase activity in urine and increase in urine output.

5) Hypoglycemic effect:

 Lignan in burdock fruit extract has a strong Ca2+ antagonist-like activity, which can significantly reduce the high blood sugar level caused by oral sugar in normal mice and the blood sugar level of alloxan type diabetes .

6) Analgesic effect: 

This product can inhibit the pain response caused by acetic acid stimulation of the abdominal mucosa, prolong the writhing latency period, and reduce the number of writhing reactions in each rat.

7) Other effects: 

Arctiin in burdock fruit extract also has the effect of dilating blood vessels, uterus, and intestines, can cause a short-term drop in blood pressure, has an anesthetic effect on motor nerves and skeletal muscles, and has a mild diarrhea effect.


Part4. Application

1. It is used for exogenous wind-heat, unfavorable cough and expectoration, and sore throat. For exogenous wind-heat and mild external heat, it can be used with mulberry leaves and chrysanthemum; for severe external heat, it can be used with honeysuckle and forsythia, such as Yinqiaosan; if wind-heat invades the lungs and unfavorable coughing, it can be used together. Campanulaceae and Fritillaria are equally used; if it is used for sore throat, it can be used with Scutellaria baicalensis, Coptis chinensis, Shegan, and Shandougen.

2. It is used for poor penetration of measles and prurigo. It is often combined with cicada slough, mint, nepeta, kudzu root, etc., such as bamboo leaf willow root soup.

3. It is especially suitable for heat-toxin carbuncle, erysipelas, mumps, and sore throat. The above-mentioned diseases are combined with wind-heat syndrome or constipation. Such as treating pyretic carbuncle, constipation, rhubarb, Glauber's salt, gardenia, forsythia, peppermint, etc.; for mastitis that has not yet become pus, honeysuckle, forsythia, gardenia, and Trichosanthes are used equally. Such as burdock seed soup.


Great Burdock Fruit Extract

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